HIV-infected infants frequently present with clinical symptoms in the first year of life. Without effective treatment, an estimated one third of infected infants will have died by one year of age, and about half will have died by two years of age. These treatment guidelines serve as a framework for selec...
For the first time, the elimination of mother-to-child transmission of HIV (MTCT) is now considered a realistic public health goal and an important part of the campaign to achieve the millennium development goals. The 2010 revised PMTCT recommendations are based on two key approaches; lifelong ART for HI...
WHO guidelines for ART for HIV infection in adults and adolescents were originally published in 2002, and were revised in 2003 and 2006. New evidence has emerged on when to initiate ART, optimal ART regimens, the management of HIV coinfection with tuberculosis and chronic viral hepatitis, and the managem...
Malnutrition is the largest single underlying cause of death worldwide and is associated with over 1/3 of all childhood deaths. The objective of the document is to provide a summary of existing WHO information regarding the principles of identification and management of communicable diseases in malnouris...
This is fourth edition of Treatment of tuberculosis: guidelines, adhering fully to the new WHO process for evidence-based guidelines. Several important recommendations are being promoted in this new edition.
First, the recommendation to discontinue the regimen based on just 2 months of rifampicin (2HRZE...
Significant programmatic experience and research evidence regarding HIV and infant
feeding have accumulated since recommendations on infant feeding in the context of
HIV were last revised in 2006. In particular, evidence has been reported that antiretroviral (ARV) interventions to either the HIV-infected...
The World Health Organization (WHO) first published guidance for national
tuberculosis control programmes on managing tuberculosis in children (hereafter
called “the Guidance”) in 2006. The Guidance follows the principles of a public
health approach aimed at optimizing outcomes, including the quality...
Malaria case management remains a vital component of the malaria control strategies.
This entails early diagnosis and prompt treatment with effective antimalarial medicines.
The WHO Guidelines for the treatment of malaria, which were first published in 2006,
provide global, evidence-based recommendations...
The purpose of this document is to provide a basis for advice to clinicians on the use of the currently available antivirals for patients presenting with illness due to influenza virus infection, as well their use for chemoprophylaxis. This guidance updates and replaces the recommendations published in A...
This revised guidance is published in two parts. Part II documents the procedures followed in developing this guidance, together with a review of evidence and other new information on the pharmacological agents considered....
